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When patients come off the medication, if theyre not supporting their initial access to medication with appropriate lifestyle, they are going to see a rapid regain in weight. As cardiovascular risk of events like heart attack and stroke starts increasing again (as shown to increase up to 22% two years out by a 2026 Washington University in St
In research, tirzepatide and semaglutide are both associated with an increased risk of gastrointestinal side effects, with tirzepatide causing more frequent disturbances (28)
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When to talk to your clinician : If youre considering tirzepatide, ask about goals, the expected timeline for results, possible side effects, drug interactions with your current medications, and insurance coverage
