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Trends in glucagon-like peptide 1 receptor agonist use, 2014 to 2022

This once-weekly injectable medication works by enhancing insulin secretion in response to meals, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways

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High circulating TMAO correlates with increased brain proinflammatory cytokines and astrocyte activation markers (144)

Consequently, miR-181b diminishes CXCL1 and CXCL-2 by interacting with their 3 UTR