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Published studies have examined its effects on glucose homeostasis, lipid metabolism, body composition, and energy expenditure in rodent and non-human primate models

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It also activates reward-related brain regions that respond to food, making food generally less appealing

Weight and hormones are deeply connected, so patients who also optimize testosterone or estrogen and progesterone where appropriate often see better body composition changes than those on medication alone

Standard titration schedule WeightCare typically starts patients at 0.25mg per week