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Mechanistically, DMF regulates the expression of factors involved in the de novo cysteine synthesis (CBS), cystine uptake (SLC7A11), and GSH generation (GCLC, GCLM) through NRF2-dependent and independent pathways

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Among the strategies developed, there are agents capable of neutralizing LPS, such as cationic lipids or cationic proteins, which are effective in binding LPS in compounds that are difficult to separate, useful to evading LPS-mediated immune stimulation

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