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More recent genome-wide analyses by Pickart and Margolina (2018) identified GHK-Cu as upregulating 84 genes while downregulating 27 genes associated with aging-related decline

GHK-Cu research often includes analytical work to confirm copper coordination (UV-Vis spectroscopy at ~525 nm, HPLC with Cu detection)

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Oxidative stress is caused by an overproduction of oxidants or unbalanced defence mechanisms played by antioxidants and their related enzymes