Common Gastrointestinal Side Effects of Semaglutide The digestive system is often the first to respond to semaglutide, leading to several notable side effects: Nausea: As one of the most common side effects, nausea is often experienced when starting semaglutide treatment or increasing the dosage
Kann et al., 2005)
That is a striking pattern
A study published in the journal Diabetes, Obesity and Metabolism found that patients on once-weekly semaglutide experienced significant decreases in serum B12 levels alongside reductions in zinc and albumin
Across online communities, however, one of the most consistently reported symptoms is a mouth that suddenly feels parched, sometimes mildly, sometimes severely enough to wake people at night or make eating uncomfortable
During pregnancy, B12 works alongside folate in neural tube formation and rapid cell division