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In line with the role of mTOR as a master metabolic regulator, rapamycin-treated enriched CAR T cells showed significant decrease in basal respiration (Fig
The only downside was how difficult it was to tear open, but this ensures the product stays sealed and sterile until use
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For example, initial treatment consists of a three-drug regimen, such as bortezomib (a proteasome inhibitor), lenalidomide, and dexamethasone (VRd) (Richardson et al., 2010)
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