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Whether this should be regarded as specific metabolic treatment, targeting only the metabolic alterations of the syndrome, is debatable, since the improvement in metabolic conditions, e.g., insulin resistance, would tenably have a positive impact also in gonadal function in women with PCOS

And dont forget: this is about more than just losing weight

This thermal effect is not dangerous

In principle, sphingomyelin can be hydrolyzed by different enzymes: neutral SMase, acidic SMase, and secreted forms of SMases [120]

Circulation 146 , 13831405 (2022)

The SURPASS-2 trialis a testament to its prowess, showcasing significant outperformance in reducing A1C levels over semaglutide