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The metformin dosage was calibrated and adjusted according to body surface area with reference to the human equivalent dose (1000 mg/day)
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Lyophilization is a sophisticated freeze-drying process where water is removed from the peptide under vacuum
(2005) (2 R)-4-Oxo-4-[3-(trifluoromethyl)-5, 6-dihydro [1, 2, 4] triazolo [4, 3-a] pyrazin-7 (8 H)-yl]-1-(2, 4, 5-trifluorophenyl) butan-2-amine: a Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes
W.LadensteinR.SchfferJ.GallayO.HuberR
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