It works by binding to GLP-1 receptors in the pancreas, which stimulates the release of insulin in response to food intake
Hemorrhage, necrosis, and extramedullary hematopoietic foci may be present
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In TRIUMPH-4 (obesity + knee OA): nausea 43%, diarrhea 33%, vomiting 21%, constipation 25%, dysesthesia 20.9%
It slows how quickly the stomach empties, helping meals feel more satisfying and sends signals to the brain that reduce appetite