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doi: 10.1186/s10020-023-00651-4 20 WangHLiuYLiuJZhangSLiXSunLet al

Patients with mild to moderate renal impairment typically do not require dose adjustments, as studies have shown minimal changes in drug exposure

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Eli Lilly and Company is the pharmaceutical company that makes two tirzepatide products that are approved by the Food and Drug Administration (FDA): Mounjaro, which is approved by the FDA for improving blood sugar levels in people with Type 2 diabetes, and is often prescribed off-label for weight loss Zepbound, which is FDA approved for weight loss, as well as for obstructive sleep apnea in adults with obesity Currently, there are no FDA-approved generic versions of the drugs Mounjaro or Zepbound, and there are not any other FDA-approved tirzepatide products available besides brand-name Mounjaro and Zepbound

p=0.035) and fewer drinks per drinking day (b = 0.946

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