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For instance, it may affect the metabolism of drugs that are substrates of the cytochrome P450 enzyme system, potentially altering their efficacy or toxicity
Mechanistically, an in vitro study found that exendin-4 inhibited the secretion of IL-1 and TNF- from mouse colonic smooth muscle cells (CSMCs) via the pathway mediated by cAMP and NF-B, thereby exerting anti-inflammatory effects [218]
Ongoing Care: This is not a set it and forget it program
Semaglutide-based medications, such as Ozempic and Rybelsus, and liraglutide-based medications, such as Victoza, are FDA approved to help manage blood sugar levels in people with type 2 diabetes
JAMA Neurology
Borodavkin P, Sheridan W, Coelho C, Otarija E, Zar ZM, Miras AD, McGowan B, le Roux CW, Vincent RP, Dimitriadis GK
