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Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A

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To help with explanations, a brief summary of the methionine cycle, transsulfuration pathway, and connections to the folate cycle and Betaine (GB) pathway is provided in the next paragraph, and a schematic representation in figure 1

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When flux is increased, the glutathione/GR system is likely to be increasingly solicited to provide additional support for ascorbate regeneration (Tuzet et al

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