273 Considering the strong preclinical data on GLP-1 RAs in older animals, there is an urgent need for large-scale clinical studies to evaluate their safety and effectiveness in older populations
This effect is thought to involve mechanical stimulation of visceral sensory nerves due to gastric distension, as well as delayed digestion and absorption caused by dietary fiber
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This is a key reason why this combination is a go-to in regenerative medicine for optimizing health from within
To adjust for multiple comparisons post-hoc , the Benjamini-Hochberg procedure was used since it provides better statistical power than the Bonferroni correction [25]
Lipo-C + tirzepatide Similar rationale to the semaglutide combination, potentially even more effective given tirzepatide's superior weight loss results in trials