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The most common side effects are gastrointestinal including nausea, vomiting, and diarrhoea and are typically mild to moderate, often reducing over time with dose escalation protocols

Leombruni P, Miniotti M, Colonna F, Sica C, Castelli L, Bruzzone M, Parisi S, Fusaro E, Sarzi-Puttini P, Atzeni F, Torta RG

The American College of Physicians (ACP) and American Diabetes Association (ADA) emphasize comprehensive lifestyle intervention as the foundation of obesity treatment

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Tressler CM,Jenkinson NM,Glunde K