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456,459 The STAMPEDE platform trial employs a multiarm, parallel, adaptive design with a unified master protocol to efficiently evaluate multiple prostate cancer treatment strategies, accelerating clinical evidence generation and optimizing precision therapy for high-risk patients

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Multipotent stromal cells called mesenchymal stem cells (MSCs) have the ability to differentiate into a variety of cell types, such as adipocytes, osteoblasts, and chondrocytes

The short duration limits effectiveness, but sustained-release formulations or combination with longer-acting peptides could improve outcomes while maintaining natural mechanisms