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IGF-1 plays a central role in tumor development by stimulating proliferation and inhibiting apoptosis in cancer cells. Pollak, Nature Reviews Cancer Acromegaly-Like Symptoms (Rare) In extremely high or prolonged dosesespecially when stacked with HGHIGF-1 may contribute to: Bone thickening (jaw, forehead, hands) Enlarged soft tissue Headaches or carpal tunnel symptoms These side effects mimic acromegaly , a condition caused by excessive GH/IGF-1 signaling
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Jensen and J
There is also an interesting paradox with the combination
Blood glucose values were measured by tail nick with a Bayer Contour XT glucometer at 0, 15, 30, 45, 60, and 120 min after injection
The Glucagon-Like Peptide-1 Receptoror Not
