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The ClusPro 2.0 online server, which is a fully automated server engineered for proteinprotein docking simulations, was used to undertake a molecular docking analysis of the fusion proteins against human serum albumin (HSA) and the extracellular domain of the GLP-1 receptor (ECD-GLP-1R) 76

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When to Consider Switching to Tirzepatide or Combination Therapy Tirzepatide activates both GLP-1 and GIP receptors, offering dual-pathway appetite suppression compared to semaglutide's single GLP-1 mechanism

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Shank3 can interact with other synapse-related autism-linked proteins

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