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Nunn AVW, Guy GW, Botchway SW, Bell JD

Evidence Based Women's Health Journal

While DHAR function in the ascorbate-glutathione pathway remains an outstanding candidate as a GSSG-generating enzyme, data from biochemical, transcriptomic and reverse genetics studies all suggest that other enzymes may contribute

In cases where multiple studies originated from the same cohort, the study with the larger sample size was selected

The first and rate-limiting step is catalyzed by an enzyme called glutamate-cysteine ligase (GCL), which links glutamate and cysteine together

Researchers at higher maintenance doses often prefer 20mg vials because they last longer and reduce the frequency of reconstitution