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Brennan P, Thomas G, Langdon J (2003) The role of nitric oxide in oral diseases

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Subcutaneous tissue, the fatty layer just beneath the dermis, has a lower blood supply compared to muscle tissue

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Despite lacking MC-R binding motifs, KPV exhibits significant anti-inflammatory effects, making it a promising candidate for research into peptide compounds in immune-mediated inflammatory diseases like skin conditions, bowel diseases, asthma, and arthritis