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The researchers concluded that AOD-9604 represents a promising fat-reducing alternative to growth hormone therapy without its associated metabolic risks, particularly regarding glucose regulation and IGF-1 elevation

However, when the rats were IV injected 120 microg/kg of DSIP prior to being put in hypoxic conditions it was found that the stress-induced decrease in mitochondrial respiratory activity was completely eliminated

Endocrinology , 142 (12), 5182-5189

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However, researchers note these are in vitro measurements that do not directly translate to in vivo outcomes

Michael Eisenberg from Stanford or Dr