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Improve blood sugar control and reduce the risk of complications related to diabetes

Median follow-up times were 642 days and 529 days in the GLP-1RA and DPP-4i group, respectively

In a recently completed Phase 3, double-blind, randomized, controlled trial of once-weekly tirzepatide in the treatment of obesity, tirzepatide 15 mg achieved a mean percentage change in body weight of -20.9% (-21.9 kg) over 72 weeks of treatment, suggesting that tirzepatide 15 mg is also a potential weight loss agent ( Semaglutide1.0mg and oral semaglutide 14mg was inferior to tirzepatide in reducing HbA1c and body weight but had significant advantages over other GLP-1RAs

It also supports an even-looking tone when used regularly

The theoretical case for combination is straightforward