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However, the administered NA dose was based on efficiency in hypercholesterolemia studies, therefore, an optimal NA dose for mitochondrial myopathy has to be determined, especially considering that another study found an association between metabolites of excess NA, 2PY, and 4PY, and cardiovascular disease (CVD) 245

We further demonstrated that tau phosphorylation induced by palmitoyl-L-carnitine could be mitigated by tau kinase inhibitors

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