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Both peptides are administered intranasally at doses of 300-900 g/day, bypassing first-pass metabolism and potentially achieving direct brain delivery through the nose

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Targeting interleukin-6 signaling in clinic

5.2 Physical Physical strategies involve the use of bacteria as carriers to load or anchor materials or drugs to the outer surface of the bacteria, including electroporation (Xie et al., 2021), impregnation (Kuang et al., 2023), or membrane coating (Wu et al., 2019)

The relationship between hydrogen water and GR thus appears complementary rather than competitive, with each supporting the other's role in maintaining cellular redox balance