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Because the review of 48 studies, although comprehensive, looked at a wide and diverse group of people -- from those with conditions such as diabetes and kidney disease, and those with different starting and end points and who took different medications -- the conclusions drawn also highlight its limitations

In addition to structural damage, sexual morbidity remains a major but often underappreciated consequence of brachytherapy [107, 113]

Even modest imbalances can produce symptoms ranging from mild fatigue to life-threatening cardiac arrhythmias

Given the complexity of these interactions and the limited number of high-quality longitudinal studies, further research is warranted to better characterize the psychological consequences of anabolicandrogenic steroid use in amateur sports and to inform effective prevention and clinical management strategies

Klionsky, D