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Here is what a typical timeline looks like

NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging [PMID: 40311622] Laboratory literature summary: NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging

Its common, especially during the first few months of starting the pill or changing how you take it

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Some short-term trials have shown that supplemental antioxidant vitamin intake lowers blood pressure, 106, 123, 124, 125 but the majority of long-term clinical trials did not demonstrate any antihypertensive effects of antioxidant vitamins

Changing these protocols without medical supervision can lead to unpredictable results