It binds to toxins and neutralizes free radicals, protecting cells from oxidative damage
But its also possible that GLP-1s can have a direct impact on the brain, Jari Tiihonen, MD, PhD, professor in the Department of Clinical Neuroscience at Karolinska Institutet, tells SELF
TT-OAD2 exhibits biased agonism, and kinetics of G-protein activation and signalling that are distinct from peptide agonists
Hansen L, Hartmann B, Bisgaard T, Mineo H, Jorgensen PN, and Holst JJ
Bone Marrow Transplant 6 Suppl 1:127-30, 1990
In models of PD, curcumin activates the PI3K/Akt signaling pathway, which is crucial for promoting neuronal survival, enhancing neurotrophic support and reducing inflammation and oxidative damage, thereby improving dopaminergic neuron integrity and motor behavior ( EGCG from green tea ( Camelia sinensis ) can reduce S aggregation and the loss of dopamine by inhibiting MAO-B and COMT