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Comparative work with tirzepatide further isolates the specific contribution of glucagon receptor agonism to the overall pharmacological profile

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The authors reported the following findings: The mean change in the KCCQ-CSS was 16.6 points with semaglutide and 8.7 points with placebo (estimated difference, 7.8 points), and the mean percentage change in body weight was 13.3% with semaglutide and 2.6% with placebo (estimated difference, 10.7 percentage points)

Rybelsus, the oral semaglutide tablet, is also available in Mexico