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Nocturnal enuresis (a pediatric indication - attributed to its antimuscarinic side effects) Contraindications: Drugs that inhibit monoamine oxidase (MAOI's) taken w/in 14 days, acute recovery period after a myocardial infarction, or history of drug hypersensitivity Side Effects: drowsiness dry mouth & eyes constipation orthotstatic hypotension mild tremor sweating agitation nausea tinnitus Overdose & Treatment: See Amitriptyline
Douros, J
Drug interactions represent another area of uncertainty
Spacing them aparttypically 2 to 4 hoursallows each to be absorbed independently without competing for stomach processing time
The patient was sent home with daily use of a senna derivative laxative and routine labs pending, and was scheduled for esophagogastroduodenoscopy and colonoscopy
Gastric electrical stimulation modulates neuronal activity in nucleus tractus solitarii in rats
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