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In this context, the present study adds a complementary layer by capturing metabolite profiles that reflect the integrated functional output of these processes

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As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively

PLoS Comput Biol 2007

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