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& Tarkowski, A
Metabolic stability assays measure how quickly a drug candidate is metabolized by liver enzymesa critical parameter influencing half-life, bioavailability, and dosing frequency
Soluble fibers: the fuel of GLP-1 How they work: Soluble fibers are fermented by your gut bacteria, producing short-chain fatty acids (SCFAs) that directly stimulate GLP-1-producing L cells
Carbonic anhydrase 8 (CAR8) negatively regulates GLP-1 secretion from enteroendocrine cells in response to long-chain fatty acids
Mass spectrometry (ESI-MS or MALDI) should confirm the molecular weight matches the theoretical: hexarelin MW approximately 887 Da, ipamorelin MW approximately 711 Da
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