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[22] [23] These can identify underlying conditions contributing to weight gain and inform the most appropriate treatment pathway
For the broader pipeline context around these compounds, see our investigational peptide drugs for diabetes and obesity reviews 2019-2026 guide
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Trial-Reported Endpoints by Phase Trial Lancet 2021 Phase 2 Duration 26 weeks Population Overweight/obese, no T2D (n=706) Mean Weight Loss 10.8% at 4.5 mg vs 3.0% placebo Trial Lancet 2023 Phase 2 Duration 32 weeks Population T2D + obesity (n=92) Mean Weight Loss 8.1% cagrilintide alone