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Structural Modifications & Enhanced Stability The N-terminus is modified via acetylation (addition of an acetyl group, Ac-)

In addition to influencing the process of oxidative metabolism, BHB also plays a direct role as an endogenous ligand of the hydroxycarboxylic acid receptor 2 (HCA2), whose activation by nutritional or pharmacological approaches could ameliorate neuroinflammation (40)

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Lysate was sonicated and centrifuged at 12,000 r.p.m

Patients should maintain adequate fluid intake throughout the day, with increased consumption during physical activity or warm weather