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Semaglutide and liraglutide effects on central nervous system regulation GLP-1 and GLP-1RA are involved in the activation of various central nervous system (CNS) processes, including satiety, thermogenesis, blood pressure, neurogenesis, and inflammation reduction (15)
ACS infectious diseases , 6 (7), 15581562
Zepbound is approved only for adults, but as of this writing, it is being studied for use in adolescents
Lancet 356 , 233241 (2000)
Emerging therapies mimicking the effects of amylin and glucagon-like peptide 1
GLP-1 receptors are expressed on up to 70% cerebral arterioles [18] and endothelial cells, and experimental models demonstrate that GLP-1 signaling promotes arteriolar vasodilation, improved endothelial nitric oxide signaling, and angiogenic pathways such as VEGF upregulation, all of which enhance nutrient and oxygen delivery to metabolically active brain regions [13,14]
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