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Accessed May 20, 2026

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Methylmalonic Acidemias with Homocystinuria The genetic causes of methylmalonic acidemias with homocystinuria are due to defects in the methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria gene (MMACHC), the methylmalonic aciduria and homocystinuria, cblD type gene (MMADHC), LMBR1 domain containing 1 gene (LMBRD1

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The evidence is unambiguous: refrigeration between 28C is the only validated storage condition for maintaining potency across the 2890 day use window