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10.1016/S0014-2999(97)00137-4 49 Schack-NielsenL.MichaelsenK

Presented for research literature review only Rangel-Porras RA et al

It contains a mixture of growth factors, cytokines, and healing proteins

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Patients with a history of severe gastrointestinal disease, particularly those with inflammatory bowel disease, severe gastroesophageal reflux disease, or history of pancreatitis, require careful evaluation before considering this therapy