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This can lead to oxidative stress and tissue damage
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IGF-1 is one of the primary activating signals for satellite cells, and understanding how sustained IGF1R activation affects satellite cell proliferation, differentiation, and fusion is a key question in muscle biology
It was demonstrated that curcumin-treated model rats showed increased autophagic vesicles in kidney tissues, elevated LC3 protein levels in MPC5 cells, and decreased p62, p-mTOR, p-Akt and P13K protein levels
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