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Dihexa for Dehydration & Heat Brain Fog Tied to the record-breaking June 2026 UK heatwave which broke the June temperature record three times and triggered UKHSA red heat-health alerts this review explains why heat and dehydration are among the most common and most fixable causes of brain fog

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This transparency is crucial for responsible clinical interpretation

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The liver metabolizes most circulating melatonin via CYP1A2 (and partly CYP2C19), while cells themselves convert it to AFMK and AMK, metabolites known for potent antioxidant and anti-inflammatory activity (183)

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