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However, some patients report cramping, likely due to indirect factors such as electrolyte disturbances or rapid weight loss rather than direct drug effects
Presented for research literature review only Soleo L et al
Wegovy's clinical development programme did not include combination with HCG, and the Summary of Product Characteristics (SmPC) provides no guidance on such use
Others dismiss it entirely because large-scale human clinical trials are still lacking
It does not affect the regulatory position in the United Kingdom, the European Union or anywhere else
The quantification methods for the proportions of mediation effect and the proportions suppression effect are given by IE divided by TE, and the absolute value was obtained by dividing IE by DE, respectively [49]
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