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Quantification and statistical analysis GraphPad Prism v.10.0 and Rstudio (v.2023.09.1) were used to perform statistical analysis
The tools we use to measure lean mass in clinical trials (DXA) likely overestimate the muscle component of LBM loss because they cannot distinguish liver and muscle substrate changes from actual contractile protein loss
Misuse is
J Neurosci Res (2007) 85(5):91934.10.1002/jnr.21191 8 ZeevalkGDRazmpourRBernardLP
The UK Prospective Diabetes Study (UKPDS) suggested that the rate of beta cell deterioration associated with metformin was similar to that associated with diet alone or sulfonylureas [19]
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