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Semaglutide is also a weekly injectable that mimics GLP-1

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Glossary TME Tumor microenvironment TAMs Tumor-associated macrophage NK Natural killer DC Dendritic cell TANs Tumor-associated neutrophils MDSCs Myeloid-derived suppressor cells MMP-2 Matrix metalloprotein-2 ICD Immunogenic death CSF-1R Colony-stimulating factor 1 receptor siRNA Small interfering RNA PEG Polyethylene glycol CCL2 CC motif chemokine 2 VEGF Vascular endothelial growth factor CCR2 CC motif chemokine receptor-2 TLR Toll-like receptors TAMM Tumor-associated macrophage membranes TGF- Transforming growth factor IFN- Interferon- SeNP Selenium nanoparticles NKG2D Natural killer cell group 2D shRNA Short hairpin RNA CTLs Cytotoxic T lymphocytes Ce6 Photosensitizer chlorine E6 NIR Near-infrared MOF Metal-organic framework G-MDSC Granulocyte myeloid-derived suppressor cells PI3K Phosphatidylinositol 3-kinase ICD Immunogenic cell death ROS Reactive oxygen species CXCR4 C-X-C motif chemokine receptor-4 M-MDSC Monocyte myeloid-derived suppressor cells TAD Tadalafil ICG Indole green APC Antigen-presenting cells ACT Adoptive T cell transfer LNP Liposomal nanoparticles GM-CSF Granulocyte-macrophage colony-stimulating factor G-CSF Granulocyte colony-stimulating factor CTLA-4 Cytotoxic T lymphocyte-associated protein 4 IDO1 Indoleamine 2,3-dioxygenase-1 DOX Doxorubicin PTT Photothermal therapy PDT Photodynamic therapy ICI Immune checkpoint inhibitors PD-1 Programmed cell death 1 PD-L1 Programmed death-ligand 1 MM Multiple myeloma HER2 Human epidermal growth factor receptor 2 PTEN Phosphate and tension homology deleted on chromsome ten MPE Malignant pleural effusion IL Interleukin R848 Resiquimod References 1 DaiJSuYZhongSCongLLiuBYangJet al