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313,314 Notably, many tumors adopt a partial or hybrid EMT phenotype, retaining epithelial markers while acquiring mesenchymal traits, thereby enhancing adaptability, metastatic potential, and multidrug resistance
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This is where the combination of N-Acetyl-L-Cysteine (NAC) and the amino acid glycineoften referred to as GlyNACcomes into the spotlight
Further experimentation involved Annexin V-fluorescein isothiocyanate/propidium iodide labeling and flow cytometric analysis, which suggested that AHK-Cu may have reduced the number of apoptotic DPCs, although this decrease was not statistically significant and thus not conclusively confirmed
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