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The authors point out that other classes of drugs, including those treating erectile dysfunction and an anti-arrythmic drug, have previously been found to cause NAION in some patients

Cagrilintide is an investigational drug not currently approved alone by the FDA

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Of these, dyslipidemia was found to be the most prevalent (37.0%), with hypertension (33.5%) and anxiety (27.0%) following close behind

The authors conclude that these findings highlight the therapeutic potential of selectively targeting the GLP-1 receptorTRPM5 signalling axis, paving the way for next-generation incretin-based therapies for type 2 diabetes

PMID: 9449682