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One key component of atherosclerosis is vascular smooth muscle proliferation, previous studies have demonstrated the effects of GLP-1 agonists in reducing vascular remodeling in murine models

However, in our study, these side effects were minimal and did not lead to treatment discontinuation

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Evaluation of the effect of food on the pharmacokinetics of oral semaglutide

However, a single intraplantar administration of 20 or 50 g of exendin 2029 effectively alleviated heat hyperalgesia, with complete recovery observed by Day 8 (Supplementary Fig