Stay compliant with the latest regulatory benchmarks: Read the FDA Peptide Sameness Study Requirements Major Impurity Classes Detected Using LC-MS Truncated peptides Sequence variants D-amino acid isomers Lipid chain variants Oxidation products Deamidated peptides High-resolution LC-MS workflows enable precise mass measurement and fragmentation-based identification
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Mayr JA, Feichtinger RG, Tort F, Ribes A, Sperl W
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A subset of dedifferentiated -cells were at early stage to convert into -cell in LOsG-treated animals As a subset of FoxO1-deficient -cells adapts the -cell fate, resulting in hyperglucagonemia 22 , we determined pancreatic glucagon mRNA in LOsG-treated -cells, which were associated with low or absent FoxO1 expression