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GLP-1 receptor agonists slow gastric emptying and reduce appetite, which can lead to constipation and other gastrointestinal symptoms

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Alm disso, os astrcitos, clulas essenciais para a regulao energtica cerebral, expressam GLP-1R, e sua sinalizao adequada fundamental para manter a integridade mitocondrial e a homeostase da glicose no crebro

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