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Data were collected from a 20-week pilot trial (NCT05786521), which randomized 20 older adults (72.7 4.8 years of age, 50% women, 45% Hispanic) living with prediabetes/diabetes (hemoglobin A1C 5.7%7.5%) and overweight/obesity [body mass index (BMI): 32.9 4.0 kg/m 2 ] to 1.0 mg/weekly semaglutide + lifestyle counseling (n = 10) or lifestyle counseling alone (n = 10)

These include changes to the central nervous system, irritability, fatigue, behavioral changes, tremors, headaches, problems hearing, skin damage and cognitive loss

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Needs vary, but many people find it harder to hit protein targets when appetite is reduced

Since peptides influence cellular functions and tissue repair , they should only be administered by qualified professionals