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4 A decade of progress: novel antifungal drugs targeting resistance The main mechanism of antifungal action lies in inhibiting essential molecules, such as ergosterol (azole class) or 1,3--D-glucan (echinocandins), or by binding to ergosterol (polyene class), leading to the formation of pores and altering the integrity and permeability of the cell membrane, thereby affecting the membrane or fungal cell wall

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Originally developed for cosmetic purposes, Xeomin is now used off-label to reduce the frequency and intensity of migraines by relaxing specific muscles and easing tension

Not all the news was good the study also found an increased risk of gastrointestinal disorders (a potential concern with these diseases), hypotension, syncope, arthritic disorders, nephrolithiasis, interstitial nephritis, and drug-induced pancreatitis

2023, doi: 10.1556/650.2023.32894