Using both together produces an additive benefit as demonstrated in the original Dhurat 2013 trial and now confirmed across multiple pooled studies
AOD9604 RCT summary and clinical efficacy Annals of Clinical and Laboratory Science (PubMed) Effect of intraarticular AOD9604 with hyaluronic acid in rabbit osteoarthritis model DrugBank AOD9604 drug summary
Berberine, ALA, Omega 3s Berberine is a plant-derived compound with evidence supporting improvements in insulin sensitivity, fat metabolism, and lipid profiles addressing some of the same downstream metabolic issues that AOD-9604 targets
Nuts, seeds, and leafy greens supply magnesium
In experimental models of Wilson disease, copper accumulates in the nuclear region of hepatocytes, where these metabolic nuclear receptors are primarily located [130]
On one hand, BPC-157 might reduce some of the bleeding risks associated with these medications