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Phase 2 clinical trials showed some positive outcomes, but these were not sufficiently significant over a treatment period of 7-10 days, leading to the halt of development [11, 12]

Piche T, des Varannes SB, Sacher-Huvelin S, Holst JJ, Cuber JC, Galmiche JP

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52 In addition, most cancer cells are extremely vulnerable to glucose withdrawal, 53, 54, 55, 56, 57, 58, 59 a feature they owe to metabolic reprogramming, leading to constitutively active proliferation pathways and glucose addiction

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